Itopride Impurity 18 CAS 24197-95-3(Free Base)
| CAS No. | 24197-95-3(Free Base) |
| Molecular Formula | C11H14N2O |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Itopride Impurity 18 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Itopride Impurity 18 (CAS 24197-95-3(Free Base), C11H14N2OHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Itopride Impurity 18 (C11H14N2OHCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C11H14N2O HCl |
| Molecular Weight | 226.70 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Itopride Standards
- Itopride Impurity 6 HCl (CAS 116447-22-4)
- Itopride Hydrochloride (CAS 122892-31-3)
- Itopride Impurity 5 (CAS 122892-53-9)
- Itopride (CAS 122898-67-3)
- Itopride Impurity 20 (CAS 131028-54-1)
- Itopride-D6 Hydrochloride (CAS 1346601-02-2)
- Itopride Impurity 13 (CAS 141996-98-7)
- Itopride Impurity 19 (CAS 15182-92-0)
Recommended Standards
- Dabigatran Impurity 54 (CAS 1643377-48-3)
- Upadacitinib Impurity 15 (CAS 1201187-44-1)
- Tulobuterol impurity 24 (CAS 25847-29-4)
- 2,6-Dibromo-3-fluorophenylacetonitrile (CAS 1806328-70-0)
- 4-Chloro-N-(3-fluoro-4-methylphenyl)butanamide (CAS 953746-04-8)
- 2-(Bis(benzyloxy)phosphoryl)acetic acid (CAS 53243-58-6)
- 1,3-Dibromo-2-(trifluoromethoxy)benzene (CAS 1246643-52-6)
- 1,3-Dioxaindane-5-carbothioamide (CAS 15884-65-8)
- 4'-(Difluoromethoxy)-3'-fluoro-2-(trifluoromethoxy)-1,1'-biphenyl (CAS 1261797-39-0)
- Des-Lys16-Tirzepatide (CAS CATO-CPTD788957)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com